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Clinical Study to Compare the Efficacy and Safety of Rituximab Biosimilar HLX01 and Rituximab in Combination With CHOP, in Previously Untreated Subjects With CD20+ DLBCL

Trial Profile

Clinical Study to Compare the Efficacy and Safety of Rituximab Biosimilar HLX01 and Rituximab in Combination With CHOP, in Previously Untreated Subjects With CD20+ DLBCL

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 Feb 2024

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At a glance

  • Drugs Rituximab (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Vincristine
  • Indications Diffuse large B cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Sponsors Shanghai Henlius Biotech
  • Most Recent Events

    • 24 Jan 2024 Primary endpoint has not been met. (overall survival), as per Results published in the BMC Cancer
    • 24 Jan 2024 Results from open label extension part, published in the BMC Cancer
    • 06 Nov 2019 Safety and efficacy results released at the 61st Annual Meeting and Exposition of the American Society of Hematology (ASH-Hem 2019).
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