A Phase 1 Dose Escalation Trial to Assess the Safety and Efficacy of Infectious (Replication-intact), Cryopreserved Plasmodium Falciparum Sporozoites (PfSPZ Challenge) Administered by Direct Venous Inoculation Under Chloroquine Cover (PfSPZ-CVac) on Varying Schedules in Healthy Malaria-Naïve Adults in the United States

Trial Profile

A Phase 1 Dose Escalation Trial to Assess the Safety and Efficacy of Infectious (Replication-intact), Cryopreserved Plasmodium Falciparum Sporozoites (PfSPZ Challenge) Administered by Direct Venous Inoculation Under Chloroquine Cover (PfSPZ-CVac) on Varying Schedules in Healthy Malaria-Naïve Adults in the United States

Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Dec 2017

At a glance

  • Drugs Malaria vaccine live unattenuated-Sanaria (Primary)
  • Indications Falciparum malaria
  • Focus Adverse reactions
  • Most Recent Events

    • 09 Nov 2017 Planned End Date changed from 30 Sep 2017 to 25 Jan 2018.
    • 09 Nov 2017 Planned primary completion date changed from 30 Sep 2017 to 25 Jan 2018.
    • 09 Nov 2017 Status changed from recruiting to active, no longer recruiting.
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