A 3-Part, Open-Label Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole (Moderate Inhibitor of CYP2C9 and CYP3A), Itraconazole (Strong CYP3A Inhibitor), or Rifampin (Strong CYP3A and Moderate CYP2C9 Inducer) in Healthy Subjects

Trial Profile

A 3-Part, Open-Label Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole (Moderate Inhibitor of CYP2C9 and CYP3A), Itraconazole (Strong CYP3A Inhibitor), or Rifampin (Strong CYP3A and Moderate CYP2C9 Inducer) in Healthy Subjects

Completed
Phase of Trial: Phase I

Latest Information Update: 16 Mar 2017

At a glance

  • Drugs Avatrombopag (Primary) ; Fluconazole; Itraconazole; Rifampicin
  • Indications Idiopathic thrombocytopenic purpura; Thrombocytopenia
  • Focus Pharmacokinetics
  • Sponsors Eisai Inc
  • Most Recent Events

    • 29 Dec 2016 Status changed from recruiting to completed.
    • 24 Jun 2016 New trial record
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