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A Phase II Single-arm, Open-label Monotherapy Clinical Trial of Pembrolizumab (MK-3475) in Locally Advanced/Metastatic Renal Cell Carcinoma (mRCC) (KEYNOTE-427)

Trial Profile

A Phase II Single-arm, Open-label Monotherapy Clinical Trial of Pembrolizumab (MK-3475) in Locally Advanced/Metastatic Renal Cell Carcinoma (mRCC) (KEYNOTE-427)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Sep 2023

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At a glance

  • Drugs Pembrolizumab (Primary)
  • Indications Renal cell carcinoma
  • Focus Therapeutic Use
  • Acronyms KEYNOTE-427
  • Sponsors Merck Sharp & Dohme
  • Most Recent Events

    • 11 Sep 2023 Result of pooled analysis from KEYNOTE-001,KEYNOTE-059, KEYNOTE-048, KEYNOTE-427, KEYNOTE-052, KEYNOTE-361 assessing Tumor dynamics in patients with solid tumors treated with pembrolizumab beyond disease progression published in the Cancer Cell.
    • 29 Aug 2022 This trial has been completed in Poland (Date of the global end of the trial :01-Apr-2022), according to European Clinical Trials Database record.
    • 22 Apr 2022 This trial has been completed in Germany (Global end date: 1 Apr 2022).
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