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A Randomized Phase II, 2-armed Study in Transplant Ineligible (TI) Patients With Newly Diagnosed Multiple Myeloma (NDMM) Comparing Carfilzomib + Thalidomide + Dexamethasone (KTd) Versus Carfilzomib + Lenalidomide + Dexamethasone (KRd) Induction Therapy With Respect to Response Rates and Investigating a Carfilzomib (K) Monotherapy Maintenance Strategy

Trial Profile

A Randomized Phase II, 2-armed Study in Transplant Ineligible (TI) Patients With Newly Diagnosed Multiple Myeloma (NDMM) Comparing Carfilzomib + Thalidomide + Dexamethasone (KTd) Versus Carfilzomib + Lenalidomide + Dexamethasone (KRd) Induction Therapy With Respect to Response Rates and Investigating a Carfilzomib (K) Monotherapy Maintenance Strategy

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 01 Feb 2024

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At a glance

  • Drugs Carfilzomib (Primary) ; Thalidomide (Primary) ; Dexamethasone; Lenalidomide
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms AGMT MM 02
  • Most Recent Events

    • 04 Sep 2023 Planned End Date changed from 1 Sep 2023 to 1 Mar 2024.
    • 04 Sep 2023 Planned primary completion date changed from 1 Sep 2023 to 1 Mar 2024.
    • 15 Jun 2023 Primary endpoint (Response Rates) has not been met according to result presented at the 28th Congress of the European Haematology Association.
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