Phase 1, Pharmacokinetic, dose escalation study with rolling six design to determine the Maximum Tolerated Dose of a combination of oral metronomic Vinorelbine (NAVELBINE®) and daily daily oral Propanolol (HEMANGIOL®) for cgildren and teenagers with refractory/relapsing solid tumors.

Trial Profile

Phase 1, Pharmacokinetic, dose escalation study with rolling six design to determine the Maximum Tolerated Dose of a combination of oral metronomic Vinorelbine (NAVELBINE®) and daily daily oral Propanolol (HEMANGIOL®) for cgildren and teenagers with refractory/relapsing solid tumors.

Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 27 Sep 2016

At a glance

  • Drugs Propranolol (Primary) ; Vinorelbine (Primary)
  • Indications Glioma; Solid tumours
  • Focus Adverse reactions
  • Acronyms PROVIN
  • Most Recent Events

    • 27 Sep 2016 New trial record
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