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Risk-based, Response-adapted, Phase II Open-label Trial of Nivolumab + Brentuximab Vedotin (N + Bv) for Children, Adolescents, and Young Adults With Relapsed/Refractory (R/R) CD30 + Classic Hodgkin Lymphoma (cHL) After Failure of First-line Therapy, Followed by Brentuximab + Bendamustine (Bv + B) for Participants With a Suboptimal Response (CheckMate 744: CHECKpoint Pathway and Nivolumab Clinical Trial Evaluation)

Trial Profile

Risk-based, Response-adapted, Phase II Open-label Trial of Nivolumab + Brentuximab Vedotin (N + Bv) for Children, Adolescents, and Young Adults With Relapsed/Refractory (R/R) CD30 + Classic Hodgkin Lymphoma (cHL) After Failure of First-line Therapy, Followed by Brentuximab + Bendamustine (Bv + B) for Participants With a Suboptimal Response (CheckMate 744: CHECKpoint Pathway and Nivolumab Clinical Trial Evaluation)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Apr 2024

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At a glance

  • Drugs Bendamustine (Primary) ; Brentuximab vedotin (Primary) ; Nivolumab (Primary)
  • Indications Hodgkin's disease
  • Focus Therapeutic Use
  • Acronyms CheckMate 744
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 09 Apr 2024 Planned primary completion date changed from 8 Jan 2024 to 25 Jun 2024.
    • 25 Aug 2023 Planned End Date changed from 6 Jan 2024 to 10 Nov 2024.
    • 25 Aug 2023 Planned primary completion date changed from 6 Jan 2024 to 8 Jan 2024.
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