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A Phase II Clinical Trial of Radium-223 Activity in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) With Asymptomatic Progression While on Abiraterone Acetate or Enzalutamide Besides AR-V7 Mutational Status

Trial Profile

A Phase II Clinical Trial of Radium-223 Activity in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) With Asymptomatic Progression While on Abiraterone Acetate or Enzalutamide Besides AR-V7 Mutational Status

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Aug 2022

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At a glance

  • Drugs Radium 223 chloride (Primary)
  • Indications Adenocarcinoma; Bone metastases; Prostate cancer
  • Focus Therapeutic Use
  • Acronyms EXCAAPE
  • Most Recent Events

    • 15 Aug 2022 Results published in the European Journal of Cancer
    • 23 Nov 2020 Status changed from active, no longer recruiting to completed.
    • 21 Sep 2020 Primary endpoint (Assess the efficacy of radium-223 in terms of radiological rPFS) has been met, as per results presented at the 45th European Society for Medical Oncology Congress
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