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Safety, Efficacy and Pharmacokinetic of BPI-9016M in Patients With c-Met- Dysregulated Advanced NSCLC: A Phase Ib Study,Open-label,Dose-expansion Study

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Trial Profile

Safety, Efficacy and Pharmacokinetic of BPI-9016M in Patients With c-Met- Dysregulated Advanced NSCLC: A Phase Ib Study,Open-label,Dose-expansion Study

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 27 Apr 2023

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At a glance

  • Drugs BPI 9016 (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Biomarker; Therapeutic Use
  • Sponsors Betta Pharmaceuticals Co Ltd

    • Most Recent Events

    • 11 Apr 2023 Results (n=38) assessing safety, tolerability, efficacy and pharmacokinetics (PK) of BPI-9016M, a novel tyrosine kinase inhibitor (TKI) targeting c-MET, in c-MET overexpression or MET exon 14 skipping mutation patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC published in the BMC Cancer
    • 05 Sep 2021 Planned number of patients changed from 50 to 80.
    • 05 Sep 2021 Planned End Date changed from 1 Dec 2018 to 1 Nov 2024.
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