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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs)

Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Jun 2022

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At a glance

  • Drugs Upadacitinib (Primary) ; Disease-modifying antirheumatics
  • Indications Rheumatoid arthritis
  • Focus Registrational; Therapeutic Use
  • Sponsors AbbVie
  • Most Recent Events

    • 04 Jun 2022 Results assessing safety and efficacy in Chinese subgroup (n=228) presented at the 23rd Annual Congress of the European League Against Rheumatism
    • 05 Jun 2021 Results assessing the long term efficacy and safety of upadacitinib in patients with rheumatoid arthritis up to 64 weeks, presented at the 22nd Annual Congress of the European League Against Rheumatism.
    • 29 Sep 2020 Status changed from active, no longer recruiting to completed.
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