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A PHASE 2A, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE SAFETY AND EFFICACY OF PF-06700841 IN SUBJECTS WITH MODERATE TO SEVERE PLAQUE PSORIASIS

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Trial Profile

A PHASE 2A, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE SAFETY AND EFFICACY OF PF-06700841 IN SUBJECTS WITH MODERATE TO SEVERE PLAQUE PSORIASIS

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Dec 2022

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At a glance

  • Drugs Brepocitinib (Primary)
  • Indications Plaque psoriasis
  • Focus Therapeutic Use
  • Sponsors Pfizer

    • Most Recent Events

    • 01 Dec 2022 Results (from 5 clinical trials; NCT02310750 NCT03236493 NCT03656952 NCT02969018 NCT02974868 ) assessing Population Pharmacokinetics of Oral Brepocitinib in Healthy Volunteers and Patients published in the Clinical Pharmacology in Drug Development
    • 14 Nov 2022 Results (A cross study dose response analysis of five Phase 2 studies N=218, NCT03963401; N=212, NCT02969018; N=167, NCT02958865; N=94, NCT02974868;N=100 NCT04092452 ) assessing Pharmacologic and Clinical Rationale Brepocitinib for the Treatment of Dermatomyositis presented at the ACR Convergence 2022
    • 09 Apr 2018 Status changed from active, no longer recruiting to completed.
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