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A Phase 1 / Phase 2 Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer

Trial Profile

A Phase 1 / Phase 2 Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 Mar 2023

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At a glance

  • Drugs BMX 001 (Primary) ; Cisplatin
  • Indications Carcinoma; Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Adverse reactions
  • Acronyms BMX-HN
  • Sponsors BioMimetix
  • Most Recent Events

    • 09 Jan 2023 The sequential assignment is added in the trial. The study Assessing safety of drug in which patients Experience Grade 4 or 5 also by escalating doses of BMX-001 and Each dose will be reported separately. The Incidence Radiation-induced Mucositis by Clinician Scoring is reduced from 12 months to 6 months, hence protocol was amendment.
    • 16 Nov 2022 Status changed from active, no longer recruiting to completed.
    • 26 Aug 2020 Planned End Date changed from 1 Feb 2020 to 1 Feb 2022.
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