Safety, Tolerability, Immunogenicity and Protective Efficacy Against Naturally-Transmitted Malaria of Infectious, Cryopreserved Plasmodium Falciparum Sporozoites (PfSPZ Challenge) Administered by Direct Venous Inoculation Under Chloroquine Chemoprophylaxis (PfSPZ-CVac), in Malian Adults: A Randomized, Double Blind, Placebo-Controlled Trial

Trial Profile

Safety, Tolerability, Immunogenicity and Protective Efficacy Against Naturally-Transmitted Malaria of Infectious, Cryopreserved Plasmodium Falciparum Sporozoites (PfSPZ Challenge) Administered by Direct Venous Inoculation Under Chloroquine Chemoprophylaxis (PfSPZ-CVac), in Malian Adults: A Randomized, Double Blind, Placebo-Controlled Trial

Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Aug 2017

At a glance

  • Drugs Artesunate (Primary) ; Chloroquine (Primary) ; Malaria vaccine live attenuated-Sanaria (Primary)
  • Indications Falciparum malaria
  • Focus Adverse reactions
  • Most Recent Events

    • 04 May 2017 Status changed from not yet recruiting to recruiting.
    • 21 Dec 2016 New trial record
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