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Preoperative Induction Therapy With 12 Weeks of Panitumumab in Combination With mFOLFOX-6 in an Enriched Population (Quadruple Wild-Type) of Patients With mrT3 Rectal Cancer of the Middle Third With Clear Mesorectal Fascia

Trial Profile

Preoperative Induction Therapy With 12 Weeks of Panitumumab in Combination With mFOLFOX-6 in an Enriched Population (Quadruple Wild-Type) of Patients With mrT3 Rectal Cancer of the Middle Third With Clear Mesorectal Fascia

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Sep 2023

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At a glance

  • Drugs Panitumumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms PIER
  • Most Recent Events

    • 25 Sep 2023 This trial has been discontinued, according to European Clinical Trials Database record.
    • 16 Mar 2022 Status changed from active, no longer recruiting to completed.
    • 08 Jun 2021 Primary endpoint has been met. (Pathologic complete response (pCR)) as per results presented at the 57th Annual Meeting of the American Society of Clinical Oncology.
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