A study evaluating drug plasma concentrations in pulmonary arterial hypertension patients during bosentan and sildenafil (BOS-SIL) combination treatment and changes after transition from BOS to Macitentan (MAC).

Trial Profile

A study evaluating drug plasma concentrations in pulmonary arterial hypertension patients during bosentan and sildenafil (BOS-SIL) combination treatment and changes after transition from BOS to Macitentan (MAC).

Completed
Phase of Trial: Phase I

Latest Information Update: 04 Jan 2017

At a glance

  • Drugs Bosentan (Primary) ; Macitentan (Primary) ; Sildenafil (Primary)
  • Indications Pulmonary arterial hypertension
  • Focus Pharmacokinetics
  • Most Recent Events

    • 04 Jan 2017 New trial record
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