A study evaluating drug plasma concentrations in pulmonary arterial hypertension patients during bosentan and sildenafil (BOS-SIL) combination treatment and changes after transition from BOS to Macitentan (MAC).
Phase of Trial: Phase I
Latest Information Update: 04 Jan 2017
At a glance
- Drugs Bosentan (Primary) ; Macitentan (Primary) ; Sildenafil (Primary)
- Indications Pulmonary arterial hypertension
- Focus Pharmacokinetics
- 04 Jan 2017 New trial record