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A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1, in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Trial Profile

A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1, in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Mar 2024

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At a glance

  • Drugs Cemiplimab (Primary)
  • Indications Basal cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms EMPOWER-BCC 1
  • Sponsors Regeneron Pharmaceuticals
  • Most Recent Events

    • 08 Mar 2024 This trial has been discontinued in Italy, according to the European Clinical Trials Database record.
    • 08 Dec 2023 Final results (n=54) of metastatic basal cell cancer after first-line hedgehog pathway inhibitors were published in the Annals of Oncology.
    • 05 Oct 2023 This trial has been discontinued in Spain, according to the European Clinical Trials Database record.
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