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A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 2b Efficacy Study of a Heterologous Prime/Boost Vaccine Regimen of Ad26.Mos4.HIV and Aluminum Phosphate-adjuvanted Clade C gp140 in Preventing HIV-1 Infection in Adult Women in Sub-Saharan Africa

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Trial Profile

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 2b Efficacy Study of a Heterologous Prime/Boost Vaccine Regimen of Ad26.Mos4.HIV and Aluminum Phosphate-adjuvanted Clade C gp140 in Preventing HIV-1 Infection in Adult Women in Sub-Saharan Africa

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 20 Apr 2023

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At a glance

  • Drugs Ad26 Mos4 HIV (Primary) ; Aluminium phosphate; HIV clade C gp140 vaccine
  • Indications HIV-1 infections
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Acronyms Imbokodo
  • Sponsors Janssen Vaccines and Prevention B.V

    • Most Recent Events

    • 02 Aug 2022 Results of an immune correlates analysis presented at the 24th International AIDS Conference
    • 16 Feb 2022 Results presented at the 29th Conference on Retroviruses and Opportunistic Infections
    • 18 Jan 2022 Planned End Date changed from 23 Jul 2022 to 28 Feb 2022.
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