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Neurodevelopmental Outcome After Standard Dose Sevoflurane Versus Low-dose Sevoflurane/Dexmedetomidine/Remifentanil Anaesthesia in Young Children- The TREX Trial

Trial Profile

Neurodevelopmental Outcome After Standard Dose Sevoflurane Versus Low-dose Sevoflurane/Dexmedetomidine/Remifentanil Anaesthesia in Young Children- The TREX Trial

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 16 Jul 2024

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At a glance

  • Drugs Dexmedetomidine (Primary) ; Remifentanil (Primary) ; Sevoflurane (Primary)
  • Indications Anaesthesia
  • Focus Therapeutic Use
  • Acronyms The TREX Trial

Most Recent Events

  • 01 Dec 2024 Results secondary analyses comparing incidence of intraoperative hypotension and bradycardia, postoperative pain, time to recovery, need for treatment of intraoperative hypotension and bradycardia, incidence of light anesthesia and need for treatment, need for postoperative pain medications, and morbidity and mortality outcomes at 5 days between the two arms published in the Anesthesiology.
  • 04 Jul 2024 Planned primary completion date changed from 1 Jun 2023 to 1 Mar 2026.
  • 27 Apr 2023 Status changed from recruiting to active, no longer recruiting.

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