A Randomized, Global, Phase 3 Trial of Nivolumab Plus Epacadostat in Combination With Chemotherapy (Platinum + 5-fluorouracil) Versus the EXTREME Regimen (Cetuximab + Platinum + 5-fluorouracil) in First-line Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) / CheckMate 9NA /ECHO-310

Trial Profile

A Randomized, Global, Phase 3 Trial of Nivolumab Plus Epacadostat in Combination With Chemotherapy (Platinum + 5-fluorouracil) Versus the EXTREME Regimen (Cetuximab + Platinum + 5-fluorouracil) in First-line Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) / CheckMate 9NA /ECHO-310

Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 17 Nov 2017

At a glance

  • Drugs Epacadostat (Primary) ; Cetuximab; Cisplatin; Fluorouracil; Nivolumab
  • Indications Head and neck cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Incyte Corporation
  • Most Recent Events

    • 09 Nov 2017 Status changed from planning to not yet recruiting.
    • 04 May 2017 According to an Incyte Corporation media release, this trial is expected to initiate in 2017.
    • 07 Apr 2017 New trial record
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