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An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Trial Profile

An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 11 Mar 2024

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At a glance

  • Drugs Evinacumab (Primary) ; Alirocumab
  • Indications Hyperlipoproteinaemia type IIa
  • Focus Adverse reactions; Registrational
  • Sponsors Regeneron Pharmaceuticals
  • Most Recent Events

    • 13 Nov 2023 Results (n=14 from NCT04233918 and n=14 from NCT03409744) assessing Effects of Evinacumab on Atherogenic Lipoproteins in Children and Adolescents From Ages 5 to 17 Years With Homozygous Familial Hypercholesterolemia presented at the American Heart Association Scientific Sessions 2023
    • 01 May 2023 Status changed from active, no longer recruiting to completed.
    • 09 Nov 2022 Planned End Date changed from 25 Jan 2023 to 31 May 2023.
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