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A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO -CONTROLLED, FIRST-IN-HUMAN TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF PF 06755347 AFTER SINGLE ASCENDING INTRAVENOUS AND SUBCUTANEOUS DOSING IN HEALTHY ADULT MALE PARTICIPANTS AND OPEN-LABEL AFTER SINGLE SUBCUTANEOUS DOSING IN MALE AND FEMALE PARTICIPANTS WITH PERSISTENT OR CHRONIC PRIMARY IMMUNE THROMBOCYTOPENIA

Trial Profile

A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO -CONTROLLED, FIRST-IN-HUMAN TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF PF 06755347 AFTER SINGLE ASCENDING INTRAVENOUS AND SUBCUTANEOUS DOSING IN HEALTHY ADULT MALE PARTICIPANTS AND OPEN-LABEL AFTER SINGLE SUBCUTANEOUS DOSING IN MALE AND FEMALE PARTICIPANTS WITH PERSISTENT OR CHRONIC PRIMARY IMMUNE THROMBOCYTOPENIA

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 16 Feb 2023

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At a glance

  • Drugs PF-06755347 (Primary) ; PF-06755347 (Primary)
  • Indications Chronic inflammatory demyelinating polyradiculoneuropathy; Idiopathic thrombocytopenic purpura
  • Focus Adverse reactions; First in man
  • Sponsors Pfizer
  • Most Recent Events

    • 09 Feb 2023 Status changed from recruiting to discontinued.
    • 27 Sep 2022 Planned End Date changed from 24 Nov 2023 to 24 May 2024.
    • 27 Sep 2022 Planned primary completion date changed from 24 Nov 2023 to 24 May 2024.
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