A Phase I Open-label Study to Evaluate the Effect of Multiple Doses of AZD1775 on the Pharmacokinetics of Substrates for CYP3A, CYP2C19, CYP1A2 and to Provide Data on the Effect of AZD1775 on QT Interval in Patients With Advanced Solid Tumours

Trial Profile

A Phase I Open-label Study to Evaluate the Effect of Multiple Doses of AZD1775 on the Pharmacokinetics of Substrates for CYP3A, CYP2C19, CYP1A2 and to Provide Data on the Effect of AZD1775 on QT Interval in Patients With Advanced Solid Tumours

Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Nov 2017

At a glance

  • Drugs AZD-1775 (Primary) ; Caffeine; Granisetron; Midazolam; Omeprazole
  • Indications Solid tumours
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca
  • Most Recent Events

    • 10 Nov 2017 New trial record
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