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A Double-blind, Randomized, Controlled, Phase 2/3 Study to Evaluate the Efficacy, Immunogenicity, and Safety of CpG 1018/Alum-Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine (SCB-2019) for the Prevention of SARS-CoV-2- Mediated COVID-19 in Participants Aged 12 Years and Older

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Trial Profile

A Double-blind, Randomized, Controlled, Phase 2/3 Study to Evaluate the Efficacy, Immunogenicity, and Safety of CpG 1018/Alum-Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine (SCB-2019) for the Prevention of SARS-CoV-2- Mediated COVID-19 in Participants Aged 12 Years and Older

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 11 Sep 2023

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At a glance

  • Drugs SCB 2019 (Primary) ; Alum; CpG 1018
  • Indications COVID 2019 infections
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms SPECTRA
  • Sponsors Clover Biopharmaceuticals

    • Most Recent Events

    • 03 Jul 2023 Last checked against ClinicalTrials.gov record.
    • 28 Jun 2023 Status changed from active, no longer recruiting to completed.
    • 10 Feb 2023 Results (n=30137) assessing SCB-2019 over the 6-month period following 2-dose primary vaccination series in all adult participants (Greater than 18 years of age) published in the Vaccine
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