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A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With Acute Respiratory Distress Syndrome Associated With COVID-19

Trial Profile

A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With Acute Respiratory Distress Syndrome Associated With COVID-19

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 16 May 2023

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At a glance

  • Drugs Aviptadil (Primary) ; Remdesivir (Primary)
  • Indications Adult respiratory distress syndrome; COVID 2019 infections
  • Focus Therapeutic Use
  • Acronyms ACTIV-3b; TESICO
  • Most Recent Events

    • 16 Dec 2022 Status changed to completed.
    • 07 Nov 2022 Planned primary completion date changed from 1 Oct 2022 to 30 Nov 2022.
    • 25 May 2022 Primary endpoint has not been met. (Recovery, assessed at 90 days [ Time Frame: Thru Day 90 ]), According to a NRx Pharmaceuticals media release.
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