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Master protocol of two randomized, double blind, placebo-controlled, multicenter, parallel group studies to evaluate the efficacy and safety of dupilumab in adult patients with chronic pruritus of unknown origin (CPUO)

Trial Profile

Master protocol of two randomized, double blind, placebo-controlled, multicenter, parallel group studies to evaluate the efficacy and safety of dupilumab in adult patients with chronic pruritus of unknown origin (CPUO)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Apr 2024

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At a glance

  • Drugs Dupilumab (Primary) ; Fexofenadine (Primary)
  • Indications Pruritus
  • Focus Registrational; Therapeutic Use
  • Acronyms LIBERTY-CPUO-CHIC
  • Sponsors Sanofi; Sanofi-Aventis Recherche & Developpement
  • Most Recent Events

    • 17 Nov 2022 Time frame for study A increased from week 12 to week 24.
    • 27 Oct 2022 Planned End Date changed from 13 Jun 2025 to 3 Oct 2025.
    • 09 Mar 2022 New trial record
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