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A Phase 2, 2-Part, Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis

Trial Profile

A Phase 2, 2-Part, Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 09 Sep 2025

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At a glance

  • Drugs Dupilumab (Primary)
  • Indications Eosinophilic gastroenteritis
  • Focus Therapeutic Use
  • Acronyms ENGAGE
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 06 May 2025 The protocol has been amended to change in study phase number of arms, masking type as open label, Interventional Study Model as Single Group Assignment with modification in primary endpoint.
  • 06 May 2025 Planned number of patients changed from 279 to 22.
  • 06 May 2025 Planned End Date changed from 19 Aug 2027 to 24 Mar 2027.

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