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Zolimomab aritox

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Drug Profile

Zolimomab aritox

Alternative Names: Anti-CD5 monoclonal antibody-ricin-chain-A conjugate; Anti-CD5 ricin A chain immunotoxin; CD5 Plus; CD5+; Muromonab; Orthozyme CD5 Plus; Xomazyme CD5 Plus; XZ-CD5

Latest Information Update: 24 Oct 2021

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At a glance

  • Originator Cancer Research UK
  • Developer Ortho-McNeil; XOMA
  • Class Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action CD5 antigen inhibitors; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Diabetes mellitus; Graft-versus-host disease; Renal transplant rejection; Rheumatoid arthritis

Most Recent Events

  • 28 Jun 1999 Discontinued-II for Rheumatoid arthritis in USA (Unknown route)
  • 18 Aug 1998 No-Development-Reported for Rheumatoid arthritis in USA (Unknown route)
  • 23 Aug 1996 A study in rheumatoid arthritis patients has been added to the side effects and Rheumatic Disease pharmacodynamics and therapeutic trials sections

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