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Ularitide - Cardiorentis

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Drug Profile

Ularitide - Cardiorentis

Alternative Names: ANF-95-126; ANP 95126; Atrial natriuretic factor (95-126); Atrial natriuretic factor prohormone (95-126); Atriopeptin (95-126); CDD 95-126; CDD ANP 95-126; ESP-305; Ularitide acetate; Urodilatin

Latest Information Update: 15 Feb 2023

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At a glance

  • Originator CardioPep Pharma; University of Heidelberg
  • Developer Aarhus Universitetshospital; Cardiorentis; PDL BioPharma
  • Class Amino acids; Antiasthmatics; Heart failure therapies; Natriuretic peptides; Urologics
  • Mechanism of Action Atrial peptide agonists; Diuretics
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Acute heart failure
  • Phase II Acute kidney injury; Liver cirrhosis; Pulmonary arterial hypertension
  • Discontinued Asthma; Kidney disorders

Most Recent Events

  • 15 Feb 2023 Cardiorentis temporarily halts phase II trial in Pulmonary arterial hypertension in Germany (EudraCT2020-004815-29)
  • 11 Aug 2021 Phase-II clinical trials in Pulmonary arterial hypertension (In adults, In the elderly) in Germany (IV)(EudraCT2020-004815-29)
  • 04 Aug 2021 Cardiorentis initiates enrolment in a phase II trial for pulmonary arterial hypertension in Germany (EudraCT2020-004815-29)

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