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Bucindolol - ARCA biopharma

Drug Profile

Bucindolol - ARCA biopharma

Alternative Names: BMY 13105; Bucindolol hydrochloride; Gencaro; MJ 13105; MJ 131051

Latest Information Update: 07 Aug 2019

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer ARCA biopharma Inc; Medtronic
  • Class Antiarrhythmics; Heart failure therapies; Propanolamines; Small molecules
  • Mechanism of Action Beta 1 adrenergic receptor antagonists; Beta 2 adrenergic receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Atrial fibrillation
  • Discontinued Heart failure; Myocardial infarction

Most Recent Events

  • 06 Nov 2019 ARCA Biopharma anticipates to initiate the phase III PRECISION-AF trial for Atrial fibrillation (Prevention, Recurrent) in the first quarter of 2020
  • 31 Jul 2019 The US FDA approves amendment to Special Protocol Assessment agreement for the phase III PRECISION-AF trial in Atrial fibrillation
  • 13 May 2019 ARCA biopharma files for patent protection with US PTO for bucindolol for prevention of atrial fibrillation in USA
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