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Bucindolol - ARCA biopharma Inc

Drug Profile

Bucindolol - ARCA biopharma Inc

Alternative Names: BMY 13105; Bucindolol hydrochloride; Gencaro; MJ 13105; MJ 131051

Latest Information Update: 07 Jan 2022

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer ARCA biopharma Inc; Medtronic
  • Class Anti-ischaemics; Antiarrhythmics; Benzonitrile; Heart failure therapies; Indoles; Phenyl ethers; Propanolamines; Small molecules; Vasodilators
  • Mechanism of Action Beta 1 adrenergic receptor antagonists; Beta 2 adrenergic receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Atrial fibrillation
  • Discontinued Heart failure; Myocardial infarction

Most Recent Events

  • 04 Jan 2022 Efficacy and safety data from phase IIb/III trial in Atrial fibrillation released by ARCA biopharma
  • 28 Jul 2021 Efficacy and pharmacodynamics data from a phase IIb/III trial in Atrial fibrillation released by ARCA BioPharm
  • 19 Mar 2021 ARCA Biopharma files for a patent applications for the use of bucindolol in the treatment of atrial fibrillation (AF) in patients with heart failure (HF) in undisclosed counties, prior to March 2021
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