Drug Profile
Bucindolol - ARCA biopharma Inc
Alternative Names: BMY 13105; Bucindolol hydrochloride; Gencaro; MJ 13105; MJ 131051Latest Information Update: 07 Jan 2022
Price :
$50
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At a glance
- Originator Bristol-Myers Squibb
- Developer ARCA biopharma Inc; Medtronic
- Class Anti-ischaemics; Antiarrhythmics; Benzonitrile; Heart failure therapies; Indoles; Phenyl ethers; Propanolamines; Small molecules; Vasodilators
- Mechanism of Action Beta 1 adrenergic receptor antagonists; Beta 2 adrenergic receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II/III Atrial fibrillation
- Discontinued Heart failure; Myocardial infarction
Most Recent Events
- 04 Jan 2022 Efficacy and safety data from phase IIb/III trial in Atrial fibrillation released by ARCA biopharma
- 28 Jul 2021 Efficacy and pharmacodynamics data from a phase IIb/III trial in Atrial fibrillation released by ARCA BioPharm
- 19 Mar 2021 ARCA Biopharma files for a patent applications for the use of bucindolol in the treatment of atrial fibrillation (AF) in patients with heart failure (HF) in undisclosed counties, prior to March 2021