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Drug Profile


Alternative Names: Dironyl; Dironyl maleate; Mysalfon; SH 406; Teluron; Transdihydrolisuride; VUFB 6638; ZK 31224

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Bayer HealthCare Pharmaceuticals
  • Developer Bayer Schering Pharma; Bayer Yakuhin; ErgoNex Pharma; IVAX Pharmaceuticals s.r.o.; Pfizer
  • Class Antiparkinsonians; Antipsychotics; Ergolines; Neuroprotectants; Small molecules; Urea compounds
  • Mechanism of Action Dopamine D2 receptor agonists; Serotonin 2 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hyperprolactinaemia
  • Discontinued Fibromyalgia; Fibrosis; Parkinson's disease; Pulmonary arterial hypertension; Schizophrenia

Most Recent Events

  • 11 Aug 2011 Discontinued - Phase-II for Pulmonary hypertension in Germany (unspecified route)
  • 11 Aug 2011 Discontinued - Phase-II for Pulmonary hypertension in Netherlands (unspecified route)
  • 11 Aug 2011 Discontinued - Phase-II for Pulmonary hypertension in Poland (unspecified route)
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