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Ebselen - Sound Pharmaceuticals

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Drug Profile

Ebselen - Sound Pharmaceuticals

Alternative Names: DR-3305; Ebselene; Ebseleno; Ebselenum; Harmokisane; PZ-51; SPI-1005; SPI-3005

Latest Information Update: 16 Dec 2024

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At a glance

  • Originator Nattermann
  • Developer Daiichi Sankyo Company; Medical University of South Carolina; Nattermann; Sound Pharmaceuticals; University of Oxford
  • Class Anti-ischaemics; Antiasthmatics; Antibacterials; Antiulcers; Antivirals; Azoles; Benzene derivatives; Ketones; Mood stabilisers; Neuroprotectants; Nonsteroidal anti-inflammatories; Organoselenium compounds; Small molecules; Vascular disorder therapies; Vestibular disorder therapies
  • Mechanism of Action Antioxidants; Cyclo-oxygenase 2 inhibitors; Glutathione peroxidase stimulants; Leukotriene B4 receptor antagonists; Prostaglandin receptor antagonists; Viral papain like protease inhibitors; Viral protein inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Meniere's disease
  • Phase II Bipolar disorders; COVID 2019 infections; Hearing loss; Noise-induced hearing loss; Sensorineural hearing loss; Tinnitus
  • Phase I Depressive disorders
  • Discontinued Asthma; Atherosclerosis; Cerebral infarction; Myocardial ischaemia; Peptic ulcer; Rheumatic disorders

Most Recent Events

  • 10 Dec 2024 Efficacy data from a phase III trial in Meniere’s disease released by Sound Pharmaceuticals
  • 25 Jul 2024 Sound Pharmaceuticals completes phase III STOPMD-3 trial for Meniere's-disease in USA (PO) (NCT04677972)
  • 20 May 2024 US FDA approves IND application for Ebselen treatment in Sensorineural hearing loss and cochlear implantation

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