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Ebselen - Sound Pharmaceuticals

Drug Profile

Ebselen - Sound Pharmaceuticals

Alternative Names: DR-3305; Ebselene; Ebseleno; Ebselenum; Harmokisane; PZ-51; SPI-1005; SPI-3005

Latest Information Update: 20 Sep 2019

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At a glance

  • Originator Nattermann
  • Developer Daiichi Sankyo Company; Medical University of South Carolina; Nattermann; Sound Pharmaceuticals; University of Oxford
  • Class Antiulcers; Azoles; Neuroprotectants; Nonsteroidal anti-inflammatories; Organoselenium compounds; Small molecules
  • Mechanism of Action Antioxidants; Cyclo-oxygenase 2 inhibitors; Glutathione peroxidase stimulants; Leukotriene B4 receptor antagonists; Prostaglandin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bipolar disorders; Hearing loss; Meniere's disease; Noise-induced hearing loss; Sensorineural hearing loss; Tinnitus
  • Discontinued Asthma; Atherosclerosis; Cerebral infarction; Myocardial ischaemia; Peptic ulcer; Rheumatic disorders

Most Recent Events

  • 18 Sep 2019 Ebselen - Sound Pharmaceuticals receives Fast Track designation for Meniere's disease [PO,Capsule] in USA
  • 18 Sep 2019 Sound Pharmaceuticals plans an End-of-Phase 2 meeting with the US FDA
  • 18 Sep 2019 Additional efficacy data from a phase IIb trial in Meniere's disease released by Sound Pharmaceuticals
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