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Ecopipam - Emalex Biosciences

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Drug Profile

Ecopipam - Emalex Biosciences

Alternative Names: EBS-101; Ecopipam HCl; Ecopipam Hydrochloride; PSYRX 101; SCH-39166

Latest Information Update: 06 Aug 2025

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At a glance

  • Originator Schering-Plough
  • Developer Emalex Biosciences; Psyadon Pharmaceuticals; Schering-Plough
  • Class Alcohols; Antipsychotics; Behavioural disorder therapies; Benzazepines; Cardiovascular therapies; Chlorinated hydrocarbons; Drug withdrawal therapies; Heterocyclic compounds with 4 or more rings; Naphthalenes; Obesity therapies; Small molecules
  • Mechanism of Action Dopamine D1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gilles de la Tourette's syndrome; Lesch-Nyhan syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Gilles de la Tourette's syndrome; Lesch-Nyhan syndrome
  • Phase II Speech disorders
  • Phase I/II Restless legs syndrome
  • Phase I Cardiovascular disorders
  • No development reported Gambling
  • Discontinued Cocaine-related disorders; Obesity; Schizophrenia

Most Recent Events

  • 30 Jul 2025 Emalex Biosciences plans a expanded access trial for Gilles de la Tourette's syndrome (In Child, In adolescents) (NCT07093541) (PO)
  • 28 May 2025 No recent reports of development identified for phase-I development in Speech disorders(In volunteers) in USA (PO, Tablet)
  • 05 Apr 2025 Efficacy data from phase I clinical trial in Cardiovascular disorders presented at the 77th Annual Meeting of the American Academy of Neurology 2025 (AAN-2025)

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