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Thymalfasin - SciClone Pharmaceuticals

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Drug Profile

Thymalfasin - SciClone Pharmaceuticals

Alternative Names: Thymosin-α-1; Tα 1; Zadaxin

Latest Information Update: 25 Sep 2021

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At a glance

  • Originator University of Texas at Austin
  • Developer SciClone Pharmaceuticals; sigma-tau SpA
  • Class Adjuvants; Anti-infectives; Antineoplastics; Antivirals; Oligopeptides; Thymus hormones
  • Mechanism of Action Th1 cell stimulants; Th2 cell inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer; Hepatitis B; Malignant melanoma
  • New Molecular Entity Yes
  • Available For Licensing Yes - Malignant melanoma

Highest Development Phases

  • Marketed Cancer; Hepatitis B; Hepatitis C
  • Phase III Sepsis
  • Clinical Phase Unknown COVID 2019 infections
  • Discontinued Liver cancer; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 26 Apr 2021 Clinical trials in COVID-2019 infections (Combination therapy) in China (Parenteral)
  • 08 Apr 2021 Discontinued - Phase-II for Liver cancer in USA (Intrahepatic)
  • 08 Apr 2021 Discontinued - Phase-II for Malignant melanoma in Europe (Parenteral)
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