Dexrazoxane - TopoTarget

Drug Profile

Dexrazoxane - TopoTarget

Alternative Names: ADR 529; Dexrazoxane hydrochloride; ICRF 187; KDX-0811; NSC 169780; Savene; Topotect; Totect

Latest Information Update: 10 Aug 2017

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At a glance

  • Originator TopoTarget
  • Developer Cumberland Pharmaceuticals; Kissei Pharmaceutical; Onxeo SA; TopoTarget
  • Class Adjunct therapies; Chemoprotectants; Piperazines; Small molecules
  • Mechanism of Action Iron chelating agents; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chemotherapy-induced damage
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Chemotherapy-induced damage
  • Discontinued Brain cancer

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 10 Jul 2017 Clinigen and Cumberland Pharmaceuticals obtain FDA approval for dexrazoxane for Chemotherapy induced damage in USA
  • 09 Jan 2017 Dexrazoxane licensed to Cumberland Pharmaceuticals in USA
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