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Oxaliplatin - Dr Reddy's Laboratories/Pfizer/Sanofi/Yakult Honsha

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Drug Profile

Oxaliplatin - Dr Reddy's Laboratories/Pfizer/Sanofi/Yakult Honsha

Alternative Names: 1 OHP; 1670 RB7; Ai Heng; Aiheng; Dacotin; Dacplat; Diaminocyclohexane oxalatoplatinum; Eloxatin; Eloxatine; Elplat; JM-83; NSC 266046; Oxalatoplatin; Oxalatoplatinum; RP 54780; SR 96669

Latest Information Update: 21 Jan 2025

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At a glance

  • Originator Nagoya University
  • Developer Alliance for Clinical Trials in Oncology; Beth Israel Deaconess Medical Center; Chugai Pharmaceutical; Dana-Farber Cancer Institute; Debiopharm; Pfizer; Sanofi; University of California at Irvine; University of Southern California; University of Texas M. D. Anderson Cancer Center; Yakult Honsha
  • Class Antineoplastics; Platinum complexes; Small molecules
  • Mechanism of Action DNA cross linking agents; DNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Colorectal cancer; Gastric cancer
  • Registered Liver cancer; Pancreatic cancer
  • Phase II Germ cell and embryonal neoplasms; Germ cell cancer; Intestinal cancer; Oesophageal cancer; Ovarian cancer; Testicular cancer; Uterine cancer
  • No development reported Head and neck cancer
  • Discontinued Acute myeloid leukaemia; Breast cancer; Diffuse large B cell lymphoma; Myelodysplastic syndromes; Nasopharyngeal cancer; Non-small cell lung cancer

Most Recent Events

  • 17 Jan 2025 Merck Sharp & Dohme plans a phase I/II Substudy 06E trial for Oesophageal cancer (Combination therapy, Late-stage disease, Metastatic disease) in January 2025 (NCT06780111)
  • 09 Sep 2022 Adverse events and efficacy data from a phase III ACHIEVE-2 trial in Colon cancer presented at the 47th European Society for Medical Oncology Congress (ESMO-2022)
  • 17 Feb 2021 No recent reports on development identified - Phase-II for Head and neck cancer (Adjuvant therapy) in USA (IV) (NCT00256308)

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