Onapristone - Context Therapeutics

Drug Profile

Onapristone - Context Therapeutics

Alternative Names: Apristor; AR-18; IVV-1001; Onapristone - Arno Therapeutics; Onapristone extended-release; ZK 299; ZK 98299

Latest Information Update: 04 Jan 2018

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At a glance

  • Originator Bayer Schering Pharma
  • Developer Arno Therapeutics; Bayer HealthCare Pharmaceuticals; Bayer Schering Pharma; Context Therapeutics
  • Class Antineoplastics; Antiprogestogens; Dimethylamines; Gonanes; Small molecules
  • Mechanism of Action Glucocorticoid receptor agonists; Glucocorticoid receptor antagonists; Progesterone receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Prostate cancer
  • Discontinued Breast cancer; Endometrial cancer; Endometriosis; Ovarian cancer; Pregnancy; Uterine cancer

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 16 Jan 2018 Context Therapeutics plans multiple clinical trials for Breast cancer (Metastatic disease, Monotherapy, Combination therapy, Second-line therapy or greater) by the mid of 2019
  • 22 Dec 2017 Onapristone licensed to Context Therapeutics worldwide
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