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At a glance
Originator
Indiana University; SuperGen
Developer
Eisai Co Ltd; European Organisation for Research and Treatment of Cancer; Groupe Francophone des Myelodysplasies; HOVON Foundation; Italian Group for Haematological Diseases; Janssen Pharmaceuticals; Janssen-Cilag; M. D. Anderson Cancer Center; Novartis; Otsuka Pharmaceutical; Sidney Kimmel Cancer Center; Xian-Janssen
Class
Antineoplastics; Aza compounds; Deoxyribonucleosides; Pyrimidine nucleosides; Ribonucleosides; Small molecules
Mechanism of Action
Antimetabolites; DNA methylation inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
09 Jan 2023
Efficacy data from a phase III trial in Acute myeloid leukaemia presented at the 64th American Society of Hematology Annual Meeting and Exposition(ASH-Hem-2023)
16 Aug 2022
European Organisation for Research and Treatment of Cancer (EORTC) in collaboration with Janssen Pharmaceuticals completes phase III trials in Acute myeloid leukemia in Slovakia and Bulgaria before August 2022 (IV)(EudraCT2014-001486-27)
28 Jun 2022
No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
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