Drug Profile


Alternative Names: Arava; HWA 486; SU 101

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator sanofi-aventis
  • Developer Pfizer
  • Class Antineoplastics; Disease-modifying antirheumatics; Isoxazoles; Small molecules
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors; Dihydropteroate synthase inhibitors; Epidermal growth factor receptor antagonists; Immunomodulators; Immunosuppressants; Protein tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Psoriatic arthritis; Rheumatoid arthritis
  • Discontinued Anaplastic astrocytoma; Autoimmune disorders; Cytomegalovirus infections; Glioblastoma; Graft-versus-host disease; Hypersensitivity; Immune-mediated uveitis; Multiple sclerosis; Non-small cell lung cancer; Ovarian cancer; Prostate cancer; Psoriasis; Systemic lupus erythematosus; Transplant rejection

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 01 Oct 2015 Generic equivalent available in USA for Rheumatoid arthritis
  • 26 Sep 2013 added SU101 to synonyms
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