Cidofovir
Alternative Names: Forvade®; GS 504; HPMPC; VistideLatest Information Update: 23 Sep 2021
At a glance
- Originator Institute of Organic Chemistry and Biochemistry (Prague); Rega Institute for Medical Research
- Developer Gilead Sciences; Institute of Organic Chemistry and Biochemistry (Prague); Pfizer; Rega Institute for Medical Research; University of Texas M. D. Anderson Cancer Center
- Class Antivirals; Phosphonic acids; Pyrimidinones; Small molecules
- Mechanism of Action DNA-directed DNA polymerase inhibitors; Immunomodulators
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Cytomegalovirus retinitis
- No development reported Cystitis
- Discontinued Cancer; Herpes simplex virus infections; Human papillomavirus infections; Kaposi's sarcoma; Molluscum contagiosum; Polyomavirus infections; Rheumatic disorders; Viral infections
Most Recent Events
- 04 Nov 2017 No recent reports of development identified for phase-I development in Cystitis in USA (Intravesicular, Liquid)
- 01 Dec 2016 Gilead Sciences completes a phase I trial in Cystitis (in patients who have undergone haematopoietic stem cell transplant) in USA (Intravesicular) (NCT01816646)
- 06 Sep 2013 Phase-I clinical trials in Cystitis (in patients who have undergone haematopoietic stem cell transplant) in USA (Intravesicular) (NCT01816646)