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Nesiritide - Scios

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Drug Profile

Nesiritide - Scios

Alternative Names: Brain natriuretic peptide - Scios; hBNP; JNS004; Natrecor; Noratak

Latest Information Update: 26 Dec 2022

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At a glance

  • Originator Scios
  • Developer Cilag AG; Quintiles Transnational; Scios
  • Class Heart failure therapies; Natriuretic peptides; Nerve tissue proteins
  • Mechanism of Action Diuretics; Guanylate cyclase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute heart failure
  • No development reported Cardiomyopathies; Heart failure
  • Discontinued Chronic heart failure; Postoperative hypertension

Most Recent Events

  • 05 Nov 2022 Efficacy data from a phase III ASCEND trial in Heart failure presented at the American Heart Association (ASH-2022)
  • 28 Mar 2020 Updated efficacy data from the phase III ASCEND HF trial in Acute decompensated heart failure presented at the Annual Scientific Session of the American College of Cardiology and World Congress of Cardiology Session (ACC-WCC-2020)
  • 15 Nov 2010 Efficacy and adverse events data from the phase III ASCEND-HF trial in Acute decompensated heart failure presented at the 83rd Annual Scientific Sessions of the American Heart Association

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