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Drug Profile


Alternative Names: Brain natriuretic peptide - Scios; hBNP; JNS004; Natrecor; Noratak

Latest Information Update: 08 Jun 2015

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At a glance

  • Originator Scios
  • Developer Cilag AG; Quintiles Transnational; Scios
  • Class Heart failure therapies; Natriuretic peptides; Nerve tissue proteins
  • Mechanism of Action Diuretics; Guanylate cyclase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute heart failure
  • No development reported Cardiomyopathies; Heart failure
  • Discontinued Chronic heart failure; Postoperative hypertension

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 15 Nov 2010 Efficacy and adverse events data from the phase III ASCEND-HF trial in Acute decompensated heart failure presented at the 83rd Annual Scientific Sessions of the American Heart Association
  • 30 Sep 2010 Scios completes enrolment in the phase III ASCEND-HF trial for Heart failure worldwide
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