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Olanzapine - Eli Lilly and Company

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Drug Profile

Olanzapine - Eli Lilly and Company

Alternative Names: BR-5402; LY 170053; LY-170052; Midax; Olanzapine controlled-release; Olanzapine LAI; Olanzapine long-acting; Olanzapine pamoate; Zypadhera; Zyprexa; Zyprexa Relprevv; Zyprexa Velotab; Zyprexa Zydis

Latest Information Update: 20 Feb 2025

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At a glance

  • Originator Eli Lilly and Company
  • Developer Boryung Pharmaceutical; Eli Lilly and Company
  • Class Antidepressants; Antiemetics; Antimanics; Antipsychotics; Behavioural disorder therapies; Benzodiazepines; Mood stabilisers; Piperazines; Small molecules; Thiophenes
  • Mechanism of Action Dopamine D1 receptor antagonists; Dopamine D2 receptor antagonists; Serotonin 5-HT2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Aggression; Bipolar depression; Bipolar disorders; Manic episodes; Schizophrenia
  • No development reported Anorexia nervosa; Huntington's disease; Major depressive disorder; Personality disorders

Most Recent Events

  • 12 Feb 2025 Phase-II clinical trials in Schizophrenia in South Korea (PO) (NCT06821945)
  • 07 Jan 2024 NDR batch #30: No updates; kept NDR as it is as trial completed in 2016 and Dev line is NDR from 2021 but as drug was in phase III development and no any source for discontinuation found hence not marked as discontinued mail sent to the company for confirmation
  • 23 Jul 2023 Cheplapharm acquires worldwide commercial rights to olanzapine from Eli Lilly

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