Nemorubicin

Drug Profile

Nemorubicin

Alternative Names: FCE 23762; Methoxymorpholinyl doxorubicin; PNU 152243; PNU-152243A

Latest Information Update: 21 Sep 2015

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At a glance

  • Originator Pfizer
  • Class Anthracyclines; Cytostatic antibiotics
  • Mechanism of Action DNA intercalators; DNA topoisomerase I inhibitors; RNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hepatocellular carcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatocellular carcinoma; Solid tumours

Most Recent Events

  • 22 Apr 2009 Preclinical cardiotoxicity data presented at the 100th Annual Meeting of the American Association for Cancer Research (AACR-2009)
  • 09 Nov 2007 Data presented at the 19th AACR-NCI-EORTC Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2007) added to the adverse events and Cancer therapeutic trials sections
  • 26 Apr 2007 Phase-I/II clinical trials in Hepatocellular carcinoma in European Union (Intra-arterial)
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