Drug Profile
Mifepristone - Corcept Therapeutics
Alternative Names: C 1073; Corlux; Corluxin; Korlym; Mifegyne; Mifeprex; RU 38486; RU-486Latest Information Update: 19 Dec 2018
Price :
$50
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At a glance
- Originator Roussel Uclaf; Stanford University
- Developer Corcept Therapeutics; Danco Laboratories; Population Council (USA); pSivida; Stanford University; University of Chicago
- Class Abortifacients; Antiprogestogens; Antivirals; Dimethylamines; Estrenes; Oral contraceptives; Small molecules
- Mechanism of Action Glucocorticoid receptor antagonists; Progesterone receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Cushing syndrome; Induced abortion
- Phase I/II Breast cancer; Prostate cancer
- Discontinued Alzheimer's disease; Obesity; Ocular hypertension; Psychotic affective disorders
Most Recent Events
- 13 Dec 2018 Corcept Therapeutics receives a notice of patent allowance for concomitant use of mifepristone and CYP3A inhibitors to treat patients with hypercortisolism including Cushing syndrome in USA
- 28 Mar 2018 pSivida is now called EyePoint Pharmaceuticals
- 15 Mar 2018 Corcept Therapeutics files lawsuit against Teva Pharmaceuticals for infringement of mifepristone (Korlym®) patents in USA