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Ranpirnase - Orgenesis

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Drug Profile

Ranpirnase - Orgenesis

Alternative Names: Amphibian ribonuclease A; Onconase; P-30 protein - Alfacell; P-30 ribonuclease

Latest Information Update: 28 Jul 2023

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At a glance

  • Originator Alfacell Corporation
  • Developer Alfacell Corporation; Orgenesis; Tamir Biotechnology
  • Class Antineoplastics; Antivirals; Eye disorder therapies; Ribonucleases
  • Mechanism of Action Apoptosis stimulants; Protein synthesis inhibitors; Ribonuclease replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mesothelioma; Ebola virus infections
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Genital warts
  • No development reported COVID 2019 infections; Ebola virus infections; HIV infections; Zika virus infection
  • Discontinued Acute myeloid leukaemia; Brain cancer; Chronic lymphocytic leukaemia; Mesothelioma; Neuroblastoma; Non-small cell lung cancer; Pancreatic cancer; Prostate cancer; Renal cell carcinoma

Most Recent Events

  • 28 Jul 2023 No recent reports of development identified for clinical-Phase-Unknown development in COVID-2019-infections in USA (Parenteral)
  • 28 Apr 2022 No recent reports of development identified for preclinical development in Ebola-virus-infections in USA (Parenteral)
  • 28 Apr 2022 No recent reports of development identified for preclinical development in HIV-infections in USA (Parenteral)
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