Icatibant - Shire

Drug Profile

Icatibant - Shire

Alternative Names: Firazyr; HOE-140; Icatibant; Icatibant acetate; JE-049; SHP-667

Latest Information Update: 25 Sep 2018

Price : $50 *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator sanofi-aventis
  • Developer Jerini; sanofi-aventis; Shire
  • Class Analgesics; Antiallergics; Antiarrhythmics; Cardiovascular therapies; Vascular disorder therapies
  • Mechanism of Action Bradykinin B2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Capillary leak syndrome; Hereditary angioedema
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hereditary angioedema
  • Preregistration Submission Withdrawal Angioedema
  • No development reported Capillary leak syndrome; Liver cirrhosis
  • Discontinued Arrhythmias; Musculoskeletal pain; Myocardial infarction; Pancreatitis; Rhinitis

Most Recent Events

  • 21 Sep 2018 Efficacy and safety data from a phase III trial in Hereditary Angioedema in Japan released by Shire
  • 21 Sep 2018 Shire completes a phase III trial for Hereditary angioedema (HAE) attacks in Japan, prior to September 2018
  • 21 Sep 2018 Registered for Hereditary angioedema (In adults) in Japan (SC)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top