Drug Profile


Alternative Names: D-1694; ICI-D1694; Tomudex; ZD 1694; ZN-D1694

Latest Information Update: 24 Mar 2018

Price : *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator The Institute of Cancer Research
  • Developer AstraZeneca; Centre Georges Francois Leclerc; Hospira; National Cancer Institute (France)
  • Class Antineoplastics; Quinazolines; Small molecules; Thiophenes
  • Mechanism of Action Thymidylate synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Colorectal cancer; Mesothelioma

Most Recent Events

  • 21 Jun 2017 Phase-II development for Colorectal cancer in patients with unresectable liver metastases is ongoing in France (Intra-arterial) (NCT01348412)
  • 03 Sep 2015 Hospira has been acquired by Pfizer
  • 01 Dec 2010 Phase-II clinical trials in Colorectal cancer (Combination therapy, Second-line therapy or greater, Metastatic disease) in France (Intra-arterial) (NCT01348412)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top